International reports

The Dangers of Sitting at Work and Standing - TIME    

Standing desks are in. Once the province of a few dynamic individuals like Winston Churchill, Ernest Hemingway and Donald Rumsfeld (O.K., two out of three ain't bad), the stand-up desk is spreading to the world of corporate drones. And for good reason — there’s a growing body of medical evidence that hours of uninterrupted sitting can be surprisingly bad for your health.
http://healthland.time.com/2011/04/13/the-dangers-of-sitting-at-work%E2%80%94and-standing/

Stand up at office to lose weight, says exercise scientist

Office workers trapped behind their desks all day should push away their chairs and work standing up, recommends an exercise scientist.
http://www.bbc.co.uk/news/education-20947605

The Risks of a Sedentary Lifestyle: Stand up for Your Health

Spending hours on end in a chair isn't just murder on your back—it can literally kill you. And if you're like the average person, you clock almost 55 hours a week on your duff. Shockingly, working out isn't an antidote. Here, what is.
http://www.womenshealthmag.com/health/standing-desk


Your Office Chair Is Killing You - Business Week

"When you're sitting, you're bearing all that weight through the pelvis and spine, and it puts the highest pressure on your back discs. Looking at MRIs, even sitting with perfect posture causes serious pressure on your back." Dr. Andrew C, Hecht, co-chief of spinal surgery at Mount Sinai Medical Center
http://www.businessweek.com/magazine/content/10_19/b4177071221162.htm

Can your desk help you lose weight?

James Levine has reviewed the statistics: One in three Minnesota adults is either diabetic or prediabetic, and one in four is obese.And he thinks he's found the underlying ailment: "The sitting disease." "Sitting is sort of the new smoking," the Mayo Clinic endocrinologist said Wednesday on the eve of an experiment designed to tackle so-called "lifestyle" diseases.
http://seattletimes.nwsource.com/html/health/2017392170_webdesk03.html 

Get off that deadly chair: Sitting too long raises fatality risk, experts say

Scientists are increasingly warning that sitting for prolonged periods — even if you also exercise regularly — could be bad for your health. And it doesn't matter where the sitting takes place — at the office, at school, in the car or before a computer or TV — just the overall number of hours it occurs.
Get up off your chair -- your life is at stake, a new study suggests.
Sitting more than six hours a day raises your risk of death, 
even if you work out, said the study, published in the American Journal of Epidemiology.

Sitting in front of desk too long. The Effect

The aforementioned problems are very common among desk bound and computer users, unfortunately the situation is not quickly discovered, though the problem is cumulative and hence there is a gradual deterioration which can be quickly rectified at any stage (not always, but in most cases this holds true.
http://thehealthblogger.com/sitting-in-front-of-the-computer-for-too-long-the-effects-part-1/